The long form of pVHL is artifactually modified by serine protease inhibitor AEBSF

von Hippel–Lindau protein (pVHL) is the tumor suppressor responsible for ubiquitylating the hypoxia‐inducible factor (HIF) family of transcription factors for degradation under normoxic conditions. There are two major pVHL isoforms with the shorter isoform (pVHL(19)) lacking the acidic domain presen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Protein Sci
Prif Awduron: Tarade, Daniel, He, Shelley, St‐Germain, Jonathan, Petroff, Avi, Murphy, Anya, Raught, Brian, Ohh, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley & Sons, Inc. 2020
Pynciau:
For the Record
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380668/
https://ncbi.nlm.nih.gov/pubmed/32535973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3898
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