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The long form of pVHL is artifactually modified by serine protease inhibitor AEBSF
von Hippel–Lindau protein (pVHL) is the tumor suppressor responsible for ubiquitylating the hypoxia‐inducible factor (HIF) family of transcription factors for degradation under normoxic conditions. There are two major pVHL isoforms with the shorter isoform (pVHL(19)) lacking the acidic domain presen...
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| 出版年: | Protein Sci |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley & Sons, Inc.
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7380668/ https://ncbi.nlm.nih.gov/pubmed/32535973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3898 |
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