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The long form of pVHL is artifactually modified by serine protease inhibitor AEBSF
von Hippel–Lindau protein (pVHL) is the tumor suppressor responsible for ubiquitylating the hypoxia‐inducible factor (HIF) family of transcription factors for degradation under normoxic conditions. There are two major pVHL isoforms with the shorter isoform (pVHL(19)) lacking the acidic domain presen...
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| Publicado no: | Protein Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7380668/ https://ncbi.nlm.nih.gov/pubmed/32535973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3898 |
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