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ID: 203: Middle East respiratory syndrome coronavirus accessory protein NS4b is a 2H-Phosphoesterase that degrades 2′,5′-oligoadenylate activators of RNase L
Efficient and productive virus infection often requires viral countermeasures that block innate immunity. The interferon-inducible 2′,5′-oligoadenylate (2-5A) synthetases (OAS) and ribonuclease L (RNase L) are components of a potent host antiviral pathway. We previously showed that murine coronaviru...
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| Udgivet i: | Cytokine |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier Science Ltd
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7129261/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2015.08.207 |
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