ID: 203: Middle East respiratory syndrome coronavirus accessory protein NS4b is a 2H-Phosphoesterase that degrades 2′,5′-oligoadenylate activators of RNase L

Ítems similars

• Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation
  per: Thornbrough, Joshua M., et al.
  Publicat: (2016)
• Lineage A Betacoronavirus NS2 Proteins and the Homologous Torovirus Berne pp1a Carboxy-Terminal Domain Are Phosphodiesterases That Antagonize Activation of RNase L
  per: Goldstein, Stephen A., et al.
  Publicat: (2017)
• Structural Basis for 2′-5′-Oligoadenylate Binding and Enzyme Activity of a Viral RNase L Antagonist
  per: Ogden, Kristen M., et al.
  Publicat: (2015)
• Nucleoside modifications in RNA limit activation of 2′-5′-oligoadenylate synthetase and increase resistance to cleavage by RNase L
  per: Anderson, Bart R., et al.
  Publicat: (2011)
• Antagonism of the Interferon-Induced OAS-RNase L Pathway by Murine Coronavirus ns2 Protein Is Required for Virus Replication and Liver Pathology
  per: Zhao, Ling, et al.
  Publicat: (2012)