Lineage A Betacoronavirus NS2 Proteins and the Homologous Torovirus Berne pp1a Carboxy-Terminal Domain Are Phosphodiesterases That Antagonize Activation of RNase L

Viruses in the family Coronaviridae, within the order Nidovirales, are etiologic agents of a range of human and animal diseases, including both mild and severe respiratory diseases in humans. These viruses encode conserved replicase and structural proteins as well as more diverse accessory proteins,...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Goldstein, Stephen A., Thornbrough, Joshua M., Zhang, Rong, Jha, Babal K., Li, Yize, Elliott, Ruth, Quiroz-Figueroa, Katherine, Chen, Annie I., Silverman, Robert H., Weiss, Susan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309944/
https://ncbi.nlm.nih.gov/pubmed/28003490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02201-16
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