Lineage A Betacoronavirus NS2 Proteins and the Homologous Torovirus Berne pp1a Carboxy-Terminal Domain Are Phosphodiesterases That Antagonize Activation of RNase L

Viruses in the family Coronaviridae, within the order Nidovirales, are etiologic agents of a range of human and animal diseases, including both mild and severe respiratory diseases in humans. These viruses encode conserved replicase and structural proteins as well as more diverse accessory proteins,...

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Publicado en:J Virol
Autores principales: Goldstein, Stephen A., Thornbrough, Joshua M., Zhang, Rong, Jha, Babal K., Li, Yize, Elliott, Ruth, Quiroz-Figueroa, Katherine, Chen, Annie I., Silverman, Robert H., Weiss, Susan R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309944/
https://ncbi.nlm.nih.gov/pubmed/28003490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02201-16
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