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ID: 203: Middle East respiratory syndrome coronavirus accessory protein NS4b is a 2H-Phosphoesterase that degrades 2′,5′-oligoadenylate activators of RNase L

Efficient and productive virus infection often requires viral countermeasures that block innate immunity. The interferon-inducible 2′,5′-oligoadenylate (2-5A) synthetases (OAS) and ribonuclease L (RNase L) are components of a potent host antiviral pathway. We previously showed that murine coronaviru...

詳細記述

保存先:
書誌詳細
出版年:Cytokine
主要な著者: Jha, Babal K., Thornbrough, Joshua M., Goldstein, Stephen A., Elliott, Ruth, Weiss, Susan R., Silverman, Robert H.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier Science Ltd 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7129261/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2015.08.207
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