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Zebrafish MITF-low melanoma subtype models reveal transcriptional subclusters and MITF-independent residual disease

The MITF-low melanoma transcriptional signature is predictive of poor outcomes for patients but little is known about its biological significance and animal models are lacking. Here, we used zebrafish genetic models with low activity of Mitfa (MITF-low) and established that the MITF-low state is cau...

詳細記述

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書誌詳細
出版年:Cancer Res
主要な著者: Travnickova, Jana, Wojciechowska, Sonia, Khamseh, Ava, Gautier, Philippe, Brown, Daniel V., Lefevre, Thomas, Brombin, Alessandro, Ewing, Ailith, Capper, Amy, Spitzer, Michaela, Dilshat, Ramile, Semple, Colin A., Mathers, Marie E., Lister, James A., Steingrimsson, Eiríkur, Voet, Thierry, Ponting, Chris P., Patton, E. Elizabeth
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116150/
https://ncbi.nlm.nih.gov/pubmed/31582381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-0037
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