MITF has a central role in regulating starvation-induced autophagy in melanoma

The MITF transcription factor is a master regulator of melanocyte development and a critical factor in melanomagenesis. The related transcription factors TFEB and TFE3 regulate lysosomal activity and autophagy processes known to be important in melanoma. Here we show that MITF binds the CLEAR-box el...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Möller, Katrin, Sigurbjornsdottir, Sara, Arnthorsson, Asgeir O., Pogenberg, Vivian, Dilshat, Ramile, Fock, Valerie, Brynjolfsdottir, Solveig H., Bindesboll, Christian, Bessadottir, Margret, Ogmundsdottir, Helga M., Simonsen, Anne, Larue, Lionel, Wilmanns, Matthias, Thorsson, Vesteinn, Steingrimsson, Eirikur, Ogmundsdottir, Margret H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355916/
https://ncbi.nlm.nih.gov/pubmed/30705290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37522-6
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