MITF reprograms the extracellular matrix and focal adhesion in melanoma

The microphthalmia-associated transcription factor (MITF) is a critical regulator of melanocyte development and differentiation. It also plays an important role in melanoma where it has been described as a molecular rheostat that, depending on activity levels, allows reversible switching between dif...

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Veröffentlicht in:eLife
Hauptverfasser: Dilshat, Ramile, Fock, Valerie, Kenny, Colin, Gerritsen, Ilse, Lasseur, Romain Maurice Jacques, Travnickova, Jana, Eichhoff, Ossia M, Cerny, Philipp, Möller, Katrin, Sigurbjörnsdóttir, Sara, Kirty, Kritika, Einarsdottir, Berglind Ósk, Cheng, Phil F, Levesque, Mitchell, Cornell, Robert A, Patton, E Elizabeth, Larue, Lionel, de Tayrac, Marie, Magnúsdóttir, Erna, Ögmundsdóttir, Margrét Helga, Steingrimsson, Eirikur
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2021
Schlagworte:
Cancer Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857731/
https://ncbi.nlm.nih.gov/pubmed/33438577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63093
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