The microphthalmia-associated transcription factor (Mitf) gene and its role in regulating eye function

Mutations in the microphthalmia-associated transcription factor (Mitf) gene can cause retinal pigment epithelium (RPE) and retinal dysfunction and degeneration. We examined retinal and RPE structure and function in 3 month old mice homo- or heterozygous or compound heterozygous for different Mitf mu...

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Udgivet i:Sci Rep
Main Authors: García-Llorca, Andrea, Aspelund, Snaefridur Gudmundsdottir, Ogmundsdottir, Margret Helga, Steingrimsson, Eiríkur, Eysteinsson, Thor
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817937/
https://ncbi.nlm.nih.gov/pubmed/31659211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51819-0
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