Zebrafish MITF-low melanoma subtype models reveal transcriptional subclusters and MITF-independent residual disease

The MITF-low melanoma transcriptional signature is predictive of poor outcomes for patients but little is known about its biological significance and animal models are lacking. Here, we used zebrafish genetic models with low activity of Mitfa (MITF-low) and established that the MITF-low state is cau...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Travnickova, Jana, Wojciechowska, Sonia, Khamseh, Ava, Gautier, Philippe, Brown, Daniel V., Lefevre, Thomas, Brombin, Alessandro, Ewing, Ailith, Capper, Amy, Spitzer, Michaela, Dilshat, Ramile, Semple, Colin A., Mathers, Marie E., Lister, James A., Steingrimsson, Eiríkur, Voet, Thierry, Ponting, Chris P., Patton, E. Elizabeth
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116150/
https://ncbi.nlm.nih.gov/pubmed/31582381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-0037
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