Phosphosite Analysis of the Cytomegaloviral mRNA Export Factor pUL69 Reveals Serines with Critical Importance for Recruitment of Cellular Proteins Pin1 and UAP56/URH49

Human cytomegalovirus (HCMV) encodes the viral mRNA export factor pUL69, which facilitates the cytoplasmic accumulation of mRNA via interaction with the cellular RNA helicase UAP56 or URH49. We reported previously that pUL69 is phosphorylated by cellular CDKs and the viral CDK-like kinase pUL97. Her...

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Vydáno v:J Virol
Hlavní autoři: Thomas, Marco, Müller, Regina, Horn, Georg, Bogdanow, Boris, Imami, Koshi, Milbradt, Jens, Steingruber, Mirjam, Marschall, Manfred, Schilling, Eva-Maria, Fossen, Torgils, Stamminger, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108844/
https://ncbi.nlm.nih.gov/pubmed/31969433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02151-19
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