Phosphosite Analysis of the Cytomegaloviral mRNA Export Factor pUL69 Reveals Serines with Critical Importance for Recruitment of Cellular Proteins Pin1 and UAP56/URH49

Human cytomegalovirus (HCMV) encodes the viral mRNA export factor pUL69, which facilitates the cytoplasmic accumulation of mRNA via interaction with the cellular RNA helicase UAP56 or URH49. We reported previously that pUL69 is phosphorylated by cellular CDKs and the viral CDK-like kinase pUL97. Her...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Thomas, Marco, Müller, Regina, Horn, Georg, Bogdanow, Boris, Imami, Koshi, Milbradt, Jens, Steingruber, Mirjam, Marschall, Manfred, Schilling, Eva-Maria, Fossen, Torgils, Stamminger, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108844/
https://ncbi.nlm.nih.gov/pubmed/31969433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02151-19
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