pUL69 of Human Cytomegalovirus Recruits the Cellular Protein Arginine Methyltransferase 6 via a Domain That Is Crucial for mRNA Export and Efficient Viral Replication

The regulatory protein pUL69 of human cytomegalovirus acts as a viral mRNA export factor, facilitating the cytoplasmic accumulation of unspliced RNA via interaction with the cellular mRNA export factor UAP56. Here we provide evidence for a posttranslational modification of pUL69 via arginine methyla...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Thomas, Marco, Sonntag, Eric, Müller, Regina, Schmidt, Stefanie, Zielke, Barbara, Fossen, Torgils, Stamminger, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542374/
https://ncbi.nlm.nih.gov/pubmed/26178996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01399-15
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