Phosphosite Analysis of the Cytomegaloviral mRNA Export Factor pUL69 Reveals Serines with Critical Importance for Recruitment of Cellular Proteins Pin1 and UAP56/URH49

Human cytomegalovirus (HCMV) encodes the viral mRNA export factor pUL69, which facilitates the cytoplasmic accumulation of mRNA via interaction with the cellular RNA helicase UAP56 or URH49. We reported previously that pUL69 is phosphorylated by cellular CDKs and the viral CDK-like kinase pUL97. Her...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Thomas, Marco, Müller, Regina, Horn, Georg, Bogdanow, Boris, Imami, Koshi, Milbradt, Jens, Steingruber, Mirjam, Marschall, Manfred, Schilling, Eva-Maria, Fossen, Torgils, Stamminger, Thomas
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2020
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108844/
https://ncbi.nlm.nih.gov/pubmed/31969433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02151-19
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