Phenotypical Characterization of the Nuclear Egress of Recombinant Cytomegaloviruses Reveals Defective Replication upon ORF-UL50 Deletion but Not pUL50 Phosphosite Mutation

Nuclear egress is a common herpesviral process regulating nucleocytoplasmic capsid release. For human cytomegalovirus (HCMV), the nuclear egress complex (NEC) is determined by the pUL50-pUL53 core that regulates multicomponent assembly with NEC-associated proteins and capsids. Recently, NEC crystal...

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Publicado no:Viruses
Main Authors: Häge, Sigrun, Sonntag, Eric, Svrlanska, Adriana, Borst, Eva Maria, Stilp, Anne-Charlotte, Horsch, Deborah, Müller, Regina, Kropff, Barbara, Milbradt, Jens, Stamminger, Thomas, Schlötzer-Schrehardt, Ursula, Marschall, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7911381/
https://ncbi.nlm.nih.gov/pubmed/33499341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13020165
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