Transmembrane Protein pUL50 of Human Cytomegalovirus Inhibits ISGylation by Downregulating UBE1L

Interferon-stimulated gene 15 (ISG15) encodes a ubiquitin-like protein that can be conjugated to proteins via an enzymatic cascade involving the E1, E2, and E3 enzymes. ISG15 expression and protein ISGylation modulate viral infection; however, the viral mechanisms regulating the function of ISG15 an...

Full description

Saved in:
Bibliographic Details
Published in:J Virol
Main Authors: Lee, Myoung Kyu, Kim, Ye Ji, Kim, Young-Eui, Han, Tae-Hee, Milbradt, Jens, Marschall, Manfred, Ahn, Jin-Hyun
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052311/
https://ncbi.nlm.nih.gov/pubmed/29743376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00462-18
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items