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Crystal Structure of the Human Cytomegalovirus pUL50-pUL53 Core Nuclear Egress Complex Provides Insight into a Unique Assembly Scaffold for Virus-Host Protein Interactions

Nuclear replication of cytomegalovirus relies on elaborate mechanisms of nucleocytoplasmic egress of viral particles. Thus, the role of two essential and conserved viral nuclear egress proteins, pUL50 and pUL53, is pivotal. pUL50 and pUL53 heterodimerize and form a core nuclear egress complex (NEC),...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Walzer, Sascha A., Egerer-Sieber, Claudia, Sticht, Heinrich, Sevvana, Madhumati, Hohl, Katharina, Milbradt, Jens, Muller, Yves A., Marschall, Manfred
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645997/
https://ncbi.nlm.nih.gov/pubmed/26432641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C115.686527
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