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Crystal Structure of the Human Cytomegalovirus pUL50-pUL53 Core Nuclear Egress Complex Provides Insight into a Unique Assembly Scaffold for Virus-Host Protein Interactions

Nuclear replication of cytomegalovirus relies on elaborate mechanisms of nucleocytoplasmic egress of viral particles. Thus, the role of two essential and conserved viral nuclear egress proteins, pUL50 and pUL53, is pivotal. pUL50 and pUL53 heterodimerize and form a core nuclear egress complex (NEC),...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Walzer, Sascha A., Egerer-Sieber, Claudia, Sticht, Heinrich, Sevvana, Madhumati, Hohl, Katharina, Milbradt, Jens, Muller, Yves A., Marschall, Manfred
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645997/
https://ncbi.nlm.nih.gov/pubmed/26432641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C115.686527
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