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Human Cytomegalovirus Replication Is Strictly Inhibited by siRNAs Targeting UL54, UL97 or UL122/123 Gene Transcripts

Human cytomegalovirus (HCMV) causes severe sequelae in immunocompromised hosts. Current antiviral therapies have serious adverse effects, with treatment in many clinical settings problematic, making new therapeutic approaches necessary. We examined the in vitro efficacy of small interfering RNAs (si...

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Bibliografiske detaljer
Main Authors: Hamilton, Stuart T., Milbradt, Jens, Marschall, Manfred, Rawlinson, William D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041654/
https://ncbi.nlm.nih.gov/pubmed/24887060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097231
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