The Cytomegalovirus Protein Kinase pUL97: Host Interactions, Regulatory Mechanisms and Antiviral Drug Targeting

Human cytomegalovirus (HCMV) expresses a variety of viral regulatory proteins that undergo close interaction with host factors including viral-cellular multiprotein complexes. The HCMV protein kinase pUL97 represents a viral cyclin-dependent kinase ortholog (vCDK) that determines the efficiency of H...

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Hlavní autoři: Mirjam Steingruber, Manfred Marschall
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2020-04-01
Edice:Microorganisms
Témata:
human cytomegalovirus (HCMV)
protein kinase pUL97
kinase-host interactions
cyclin/cyclin-dependent kinase complexes
regulatory mechanisms
antiviral drugs
On-line přístup:https://www.mdpi.com/2076-2607/8/4/515
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