Risultati della ricerca - Manfred Marschall

The Cytomegalovirus Protein Kinase pUL97: Host Interactions, Regulatory Mechanisms and Antiviral Drug Targeting di Mirjam Steingruber, Manfred Marschall

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The Current Status of <i>Herpesviridae</i> as Major Human Pathogens: A 10-Year Diagnostic Evaluation in Germany di Lucio Fortelny, Manfred Marschall

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‘Come together’—The Regulatory Interaction of Herpesviral Nuclear Egress Proteins Comprises Both Essential and Accessory Functions di Sigrun Häge, Manfred Marschall

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The Oligomeric Assemblies of Cytomegalovirus Core Nuclear Egress Proteins Are Associated with Host Kinases and Show Sensitivity to Antiviral Kinase Inhibitors di Jintawee Kicuntod, Sigrun Häge, Friedrich Hahn, Heinrich Sticht, Manfred Marschall

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Human cytomegalovirus (CMV) dysregulates neurodevelopmental pathways in cerebral organoids di Ece Egilmezer, Stuart T. Hamilton, Charles S. P. Foster, Manfred Marschall, William D. Rawlinson

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Recombinant Human Cytomegalovirus Expressing an Analog-Sensitive Kinase pUL97 as Novel Tool for Functional Analyses di Nadine Krämer, Martin Schütz, Uxía Gestal Mato, Lina Herhaus, Manfred Marschall, Christine Zimmermann

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‘Shared-Hook’ and ‘Changed-Hook’ Binding Activities of Herpesviral Core Nuclear Egress Complexes Identified by Random Mutagenesis di Josephine Lösing, Sigrun Häge, Martin Schütz, Sabrina Wagner, Julia Wardin, Heinrich Sticht, Manfred Marschall

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The Trimeric Artesunate Analog TF27, a Broadly Acting Anti-Infective Model Drug, Exerts Pronounced Anti-SARS-CoV-2 Activity Spanning Variants and Host Cell Types di Friedrich Hahn, Christina Wangen, Sigrun Häge, Lars Herrmann, Alexandra Herrmann, Svetlana B. Tsogoeva, Manfred Marschall

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Functional Relevance of the Interaction between Human Cyclins and the Cytomegalovirus-Encoded CDK-Like Protein Kinase pUL97 di Martin Schütz, Mirjam Steingruber, Eileen Socher, Regina Müller, Sabrina Wagner, Merle Kögel, Heinrich Sticht, Manfred Marschall

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A Peptide Inhibitor of the Human Cytomegalovirus Core Nuclear Egress Complex di Sewar Alkhashrom, Jintawee Kicuntod, Katharina Stillger, Tamara Lützenburg, Christian Anzenhofer, Ines Neundorf, Manfred Marschall, Jutta Eichler

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Antiviral Strategies Using Natural Source-Derived Sulfated Polysaccharides in the Light of the COVID-19 Pandemic and Major Human Pathogenic Viruses di Bimalendu Ray, Imran Ali, Subrata Jana, Shuvam Mukherjee, Saikat Pal, Sayani Ray, Martin Schütz, Manfred Marschall

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New Assay Systems to Characterize the Broad-Spectrum Antiherpesviral and Non-Herpesviral Activity of Cyclin-Dependent Kinase (CDK) 8 Inhibitors di Debora Obergfäll, Friedrich Hahn, Jintawee Kicuntod, Christina Wangen, Melanie Kögler, Sabrina Wagner, Benedikt Kaufer, Manfred Marschall

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Understanding the Cytomegalovirus Cyclin-Dependent Kinase Ortholog pUL97 as a Multifaceted Regulator and an Antiviral Drug Target di Manfred Marschall, Martin Schütz, Markus Wild, Eileen Socher, Christina Wangen, Kishore Dhotre, William D. Rawlinson, Heinrich Sticht

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Human Cytomegalovirus Dysregulates Cellular Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases and Sonic Hedgehog Pathway Proteins in Neural Astrocyte and Placental Models di Ece Egilmezer, Stuart T. Hamilton, Glen Lauw, Jasmine Follett, Eric Sonntag, Martin Schütz, Manfred Marschall, William D. Rawlinson

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Exploring the Human Cytomegalovirus Core Nuclear Egress Complex as a Novel Antiviral Target: A New Type of Small Molecule Inhibitors di Sewar Alkhashrom, Jintawee Kicuntod, Sigrun Häge, Johannes Schweininger, Yves A. Muller, Peter Lischka, Manfred Marschall, Jutta Eichler

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Establishment of a Luciferase-Based Reporter System to Study Aspects of Human Cytomegalovirus Infection, Replication Characteristics, and Antiviral Drug Efficacy di Julia Tillmanns, Jintawee Kicuntod, Antonia Ehring, Endrit Elbasani, Eva Maria Borst, Debora Obergfäll, Regina Müller, Friedrich Hahn, Manfred Marschall

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Properties of Oligomeric Interaction of the Cytomegalovirus Core Nuclear Egress Complex (NEC) and Its Sensitivity to an NEC Inhibitory Small Molecule di Jintawee Kicuntod, Sewar Alkhashrom, Sigrun Häge, Benedikt Diewald, Regina Müller, Friedrich Hahn, Peter Lischka, Heinrich Sticht, Jutta Eichler, Manfred Marschall

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Combined Treatment with Host-Directed and Anticytomegaloviral Kinase Inhibitors: Mechanisms, Synergisms and Drug Resistance Barriers di Markus Wild, Dubravka Karner, Jan Eickhoff, Sabrina Wagner, Jintawee Kicuntod, William Chang, Peter Barry, Stipan Jonjić, Tihana Lenac Roviš, Manfred Marschall

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Assessment of Covalently Binding Warhead Compounds in the Validation of the Cytomegalovirus Nuclear Egress Complex as an Antiviral Target di Julia Tillmanns, Sigrun Häge, Eva Maria Borst, Julia Wardin, Jan Eickhoff, Bert Klebl, Sabrina Wagner, Christina Wangen, Friedrich Hahn, Eileen Socher, Manfred Marschall

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Mass Spectrometry-Based Characterization of the Virion Proteome, Phosphoproteome, and Associated Kinase Activity of Human Cytomegalovirus di Yohann Couté, Alexandra Kraut, Christine Zimmermann, Nicole Büscher, Anne-Marie Hesse, Christophe Bruley, Marco De Andrea, Christina Wangen, Friedrich Hahn, Manfred Marschall, Bodo Plachter

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