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HIV-1 Protease Catalytic Efficiency Effects Caused by Random Single Amino Acid Substitutions
Protein evolution has occurred by successive fixation of individual mutations. The probability of fixation depends on the fitness of the mutation, and the arising variant can be deleterious, neutral, or beneficial. Despite its relevance, only few studies have estimated the distribution of fitness ef...
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| 發表在: | Mol Biol Evol |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7107532/ https://ncbi.nlm.nih.gov/pubmed/17090696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msl168 |
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