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HIV-1 Protease Catalytic Efficiency Effects Caused by Random Single Amino Acid Substitutions
Protein evolution has occurred by successive fixation of individual mutations. The probability of fixation depends on the fitness of the mutation, and the arising variant can be deleterious, neutral, or beneficial. Despite its relevance, only few studies have estimated the distribution of fitness ef...
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| Publicat a: | Mol Biol Evol |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7107532/ https://ncbi.nlm.nih.gov/pubmed/17090696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msl168 |
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