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HIV-1 Protease Catalytic Efficiency Effects Caused by Random Single Amino Acid Substitutions
Protein evolution has occurred by successive fixation of individual mutations. The probability of fixation depends on the fitness of the mutation, and the arising variant can be deleterious, neutral, or beneficial. Despite its relevance, only few studies have estimated the distribution of fitness ef...
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| Yayımlandı: | Mol Biol Evol |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7107532/ https://ncbi.nlm.nih.gov/pubmed/17090696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msl168 |
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