Neuronal CXCL10/CXCR3 Axis Mediates the Induction of Cerebral Hyperexcitability by Peripheral Viral Challenge

Peripheral infections can potently exacerbate neuropathological conditions, though the underlying mechanisms are poorly understood. We have previously demonstrated that intraperitoneal (i.p.) injection of a viral mimetic, polyinosinic-polycytidylic acid (PIC) induces a robust generation of CXCL10 ch...

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Bibliografski detalji
Izdano u:Front Neurosci
Glavni autori: Petrisko, Tiffany J., Bloemer, Jenna, Pinky, Priyanka D., Srinivas, Sriraja, Heslin, Ryan T., Du, Yifeng, Setti, Sharay E., Hong, Hao, Suppiramaniam, Vishnu, Konat, Gregory W., Reed, Miranda N.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Neuroscience
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105801/
https://ncbi.nlm.nih.gov/pubmed/32265633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00220
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