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The Role of the CXCL12/CXCR4/CXCR7 Chemokine Axis in Cancer

Chemokines are a family of small, secreted cytokines which regulate a variety of cell functions. The C-X-C motif chemokine ligand 12 (CXCL12) binds to C-X-C chemokine receptor type 4 (CXCR4) and C-X-C chemokine receptor type 7 (CXCR7). The interaction of CXCL12 and its receptors subsequently induces...

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Publicat a:Front Pharmacol
Autors principals: Shi, Yi, Riese, David J., Shen, Jianzhong
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7753359/
https://ncbi.nlm.nih.gov/pubmed/33363463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.574667
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