Neuronal CXCL10/CXCR3 Axis Mediates the Induction of Cerebral Hyperexcitability by Peripheral Viral Challenge

Peripheral infections can potently exacerbate neuropathological conditions, though the underlying mechanisms are poorly understood. We have previously demonstrated that intraperitoneal (i.p.) injection of a viral mimetic, polyinosinic-polycytidylic acid (PIC) induces a robust generation of CXCL10 ch...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Neurosci
Egile Nagusiak: Petrisko, Tiffany J., Bloemer, Jenna, Pinky, Priyanka D., Srinivas, Sriraja, Heslin, Ryan T., Du, Yifeng, Setti, Sharay E., Hong, Hao, Suppiramaniam, Vishnu, Konat, Gregory W., Reed, Miranda N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2020
Gaiak:
Neuroscience
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105801/
https://ncbi.nlm.nih.gov/pubmed/32265633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00220
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