Neuronal CXCL10/CXCR3 Axis Mediates the Induction of Cerebral Hyperexcitability by Peripheral Viral Challenge

Peripheral infections can potently exacerbate neuropathological conditions, though the underlying mechanisms are poorly understood. We have previously demonstrated that intraperitoneal (i.p.) injection of a viral mimetic, polyinosinic-polycytidylic acid (PIC) induces a robust generation of CXCL10 ch...

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Vydáno v:Front Neurosci
Hlavní autoři: Petrisko, Tiffany J., Bloemer, Jenna, Pinky, Priyanka D., Srinivas, Sriraja, Heslin, Ryan T., Du, Yifeng, Setti, Sharay E., Hong, Hao, Suppiramaniam, Vishnu, Konat, Gregory W., Reed, Miranda N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105801/
https://ncbi.nlm.nih.gov/pubmed/32265633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00220
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