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Peripherally restricted viral challenge elevates extracellular glutamate and enhances synaptic transmission in the hippocampus

Peripheral infections increase the propensity and severity of seizures in susceptible populations. We have previously shown that intraperitoneal (i.p.) injection of a viral mimic, polyinosinic-polycytidylic acid (PIC), elicits hypersusceptibility of mice to kainic acid (KA)-induced seizures. The pre...

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書目詳細資料
發表在:J Neurochem
Main Authors: Hunsberger, Holly C., Wang, Desheng, Petrisko, Tiffany J., Alhowail, Ahmad, Setti, Sharay E., Suppiramaniam, Vishnu, Konat, Gregory W., Reed, Miranda N.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936939/
https://ncbi.nlm.nih.gov/pubmed/27168075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13665
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