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Peripherally restricted viral challenge elevates extracellular glutamate and enhances synaptic transmission in the hippocampus
Peripheral infections increase the propensity and severity of seizures in susceptible populations. We have previously shown that intraperitoneal (i.p.) injection of a viral mimic, polyinosinic-polycytidylic acid (PIC), elicits hypersusceptibility of mice to kainic acid (KA)-induced seizures. The pre...
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| Veröffentlicht in: | J Neurochem |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4936939/ https://ncbi.nlm.nih.gov/pubmed/27168075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13665 |
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