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Peripheral viral challenge elevates extracellular glutamate in the hippocampus leading to seizure hypersusceptibility
Peripheral viral infections increase seizure propensity and intensity in susceptible individuals. We have modeled this comorbidity by demonstrating that the acute phase response (APR) instigated by an intraperitoneal (i.p.) injection of a viral mimetic, polyinosinic-polycytidylic acid (PIC), induces...
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| Publicado no: | J Neurochem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5395347/ https://ncbi.nlm.nih.gov/pubmed/28244106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13999 |
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