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Riluzole Rescues Alterations in Rapid Glutamate Transients in the Hippocampus of rTg4510 Mice

Those at risk for Alzheimer’s disease (AD) often exhibit hippocampal hyperexcitability in the years preceding diagnosis. Our previous work with the rTg(TauP301L)4510 tau mouse model of AD suggests that this increase in hyperexcitability is likely mediated by an increase in depolarization-evoked glut...

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Detalhes bibliográficos
Publicado no:Metab Brain Dis
Main Authors: Hunsberger, Holly C., Hickman, James E., Reed, Miranda N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864118/
https://ncbi.nlm.nih.gov/pubmed/26744018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-015-9783-9
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