Caricamento...
Progranulin mutations result in impaired processing of prosaposin and reduced glucocerebrosidase activity
Frontotemporal dementia (FTD) is a common neurogenerative disorder characterized by progressive degeneration in the frontal and temporal lobes. Heterozygous mutations in the gene encoding progranulin (PGRN) are a common genetic cause of FTD. Recently, PGRN has emerged as an important regulator of ly...
Salvato in:
| Pubblicato in: | Hum Mol Genet |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2020
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7104673/ https://ncbi.nlm.nih.gov/pubmed/31600775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz229 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|