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Expansion and preservation of the functional activity of adult hematopoietic stem cells cultured ex vivo with a histone deacetylase inhibitor

Attempts to expand ex vivo the numbers of human hematopoietic stem cells (HSCs) without compromising their marrow repopulating capacity and their ability to establish multilineage hematopoiesis has been the subject of intense investigation. Although most such efforts have focused on cord blood HSCs,...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Zimran, Eran, Papa, Luena, Djedaini, Mansour, Patel, Ami, Iancu‐Rubin, Camelia, Hoffman, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103619/
https://ncbi.nlm.nih.gov/pubmed/31950644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.19-0199
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