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Ex vivo HSC expansion challenges the paradigm of unidirectional human hematopoiesis

Understanding mechanisms that determine the behavior of human hematopoietic stem cells (HSCs) is essential for developing novel strategies to expand ex vivo the number of fully functional HSCs. In this review, we focus on the complex interplay between intrinsic mechanisms regulated by transcriptiona...

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Dades bibliogràfiques
Publicat a:Ann N Y Acad Sci
Autors principals: Papa, Luena, Djedaini, Mansour, Hoffman, Ronald
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216880/
https://ncbi.nlm.nih.gov/pubmed/31199002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.14133
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