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Mitochondrial Role in Stemness and Differentiation of Hematopoietic Stem Cells

Quiescent and self-renewing hematopoietic stem cells (HSCs) rely on glycolysis rather than on mitochondrial oxidative phosphorylation (OxPHOS) for energy production. HSC reliance on glycolysis is considered an adaptation to the hypoxic environment of the bone marrow (BM) and reflects the low energet...

詳細記述

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書誌詳細
出版年:Stem Cells Int
主要な著者: Papa, Luena, Djedaini, Mansour, Hoffman, Ronald
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381553/
https://ncbi.nlm.nih.gov/pubmed/30881461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4067162
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