Expansion and preservation of the functional activity of adult hematopoietic stem cells cultured ex vivo with a histone deacetylase inhibitor

Attempts to expand ex vivo the numbers of human hematopoietic stem cells (HSCs) without compromising their marrow repopulating capacity and their ability to establish multilineage hematopoiesis has been the subject of intense investigation. Although most such efforts have focused on cord blood HSCs,...

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Bibliografiske detaljer
Udgivet i:Stem Cells Transl Med
Main Authors: Zimran, Eran, Papa, Luena, Djedaini, Mansour, Patel, Ami, Iancu‐Rubin, Camelia, Hoffman, Ronald
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2020
Fag:
Tissue‐specific Progenitor and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103619/
https://ncbi.nlm.nih.gov/pubmed/31950644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.19-0199
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