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Expansion and preservation of the functional activity of adult hematopoietic stem cells cultured ex vivo with a histone deacetylase inhibitor

Attempts to expand ex vivo the numbers of human hematopoietic stem cells (HSCs) without compromising their marrow repopulating capacity and their ability to establish multilineage hematopoiesis has been the subject of intense investigation. Although most such efforts have focused on cord blood HSCs,...

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Dades bibliogràfiques
Publicat a:Stem Cells Transl Med
Autors principals: Zimran, Eran, Papa, Luena, Djedaini, Mansour, Patel, Ami, Iancu‐Rubin, Camelia, Hoffman, Ronald
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103619/
https://ncbi.nlm.nih.gov/pubmed/31950644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.19-0199
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