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Ex vivo HSC expansion challenges the paradigm of unidirectional human hematopoiesis

Understanding mechanisms that determine the behavior of human hematopoietic stem cells (HSCs) is essential for developing novel strategies to expand ex vivo the number of fully functional HSCs. In this review, we focus on the complex interplay between intrinsic mechanisms regulated by transcriptiona...

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Bibliografische gegevens
Gepubliceerd in:Ann N Y Acad Sci
Hoofdauteurs: Papa, Luena, Djedaini, Mansour, Hoffman, Ronald
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216880/
https://ncbi.nlm.nih.gov/pubmed/31199002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.14133
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