Differential decay of intact and defective proviral DNA in HIV-1–infected individuals on suppressive antiretroviral therapy

BACKGROUND: The relative stabilities of the intact and defective HIV genomes over time during effective antiretroviral therapy (ART) have not been fully characterized. METHODS: We used the intact proviral DNA assay (IPDA) to estimate the rate of change of intact and defective proviruses in HIV-infec...

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Vydáno v:JCI Insight
Hlavní autoři: Peluso, Michael J., Bacchetti, Peter, Ritter, Kristen D., Beg, Subul, Lai, Jun, Martin, Jeffrey N., Hunt, Peter W., Henrich, Timothy J., Siliciano, Janet D., Siliciano, Robert F., Laird, Gregory M., Deeks, Steven G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
Clinical Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101154/
https://ncbi.nlm.nih.gov/pubmed/32045386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.132997
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