Nonstructured Treatment Interruptions Are Associated With Higher Human Immunodeficiency Virus Reservoir Size Measured by Intact Proviral DNA Assay in People Who Inject Drugs

The latent reservoir for human immunodeficiency virus type 1 (HIV-1) in CD4(+) T cells is a major barrier to cure. HIV-1–infected persons who inject drugs (PWID) often struggle to maintain suppression of viremia and experience nonstructured treatment interruptions (NTIs). The effects of injecting dr...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Kirk, Gregory D, Astemborski, Jacqueline, Mehta, Shruti H, Ritter, Kristen D, Laird, Gregory M, Bordi, Rebeka, Sekaly, Rafick, Siliciano, Janet D, Siliciano, Robert F
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176633/
https://ncbi.nlm.nih.gov/pubmed/33037877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa634
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