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Selective Decay of Intact HIV-1 Proviral DNA on Antiretroviral Therapy

BACKGROUND: HIV-1 proviruses persist in people on antiretroviral therapy (ART) but most are defective and do not constitute a replication-competent reservoir. The decay of infected cells carrying intact compared with defective HIV-1 proviruses has not been well defined in people on ART. METHODS: We...

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Podrobná bibliografie
Vydáno v:J Infect Dis
Hlavní autoři: Gandhi, Rajesh T, Cyktor, Joshua C, Bosch, Ronald J, Mar, Hanna, Laird, Gregory M, Martin, Albine, Collier, Ann C, Riddler, Sharon A, Macatangay, Bernard J, Rinaldo, Charles R, Eron, Joseph J, Siliciano, Janet D, McMahon, Deborah K, Mellors, John W
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857155/
https://ncbi.nlm.nih.gov/pubmed/32823274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa532
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