Selective Decay of Intact HIV-1 Proviral DNA on Antiretroviral Therapy

BACKGROUND: HIV-1 proviruses persist in people on antiretroviral therapy (ART) but most are defective and do not constitute a replication-competent reservoir. The decay of infected cells carrying intact compared with defective HIV-1 proviruses has not been well defined in people on ART. METHODS: We...

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Détails bibliographiques
Publié dans:J Infect Dis
Auteurs principaux: Gandhi, Rajesh T, Cyktor, Joshua C, Bosch, Ronald J, Mar, Hanna, Laird, Gregory M, Martin, Albine, Collier, Ann C, Riddler, Sharon A, Macatangay, Bernard J, Rinaldo, Charles R, Eron, Joseph J, Siliciano, Janet D, McMahon, Deborah K, Mellors, John W
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Major Articles and Brief Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857155/
https://ncbi.nlm.nih.gov/pubmed/32823274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa532
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