Selective Decay of Intact HIV-1 Proviral DNA on Antiretroviral Therapy

BACKGROUND: HIV-1 proviruses persist in people on antiretroviral therapy (ART) but most are defective and do not constitute a replication-competent reservoir. The decay of infected cells carrying intact compared with defective HIV-1 proviruses has not been well defined in people on ART. METHODS: We...

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Bibliographic Details
Published in:J Infect Dis
Main Authors: Gandhi, Rajesh T, Cyktor, Joshua C, Bosch, Ronald J, Mar, Hanna, Laird, Gregory M, Martin, Albine, Collier, Ann C, Riddler, Sharon A, Macatangay, Bernard J, Rinaldo, Charles R, Eron, Joseph J, Siliciano, Janet D, McMahon, Deborah K, Mellors, John W
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857155/
https://ncbi.nlm.nih.gov/pubmed/32823274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa532
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