Differential decay of intact and defective proviral DNA in HIV-1–infected individuals on suppressive antiretroviral therapy

BACKGROUND: The relative stabilities of the intact and defective HIV genomes over time during effective antiretroviral therapy (ART) have not been fully characterized. METHODS: We used the intact proviral DNA assay (IPDA) to estimate the rate of change of intact and defective proviruses in HIV-infec...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Peluso, Michael J., Bacchetti, Peter, Ritter, Kristen D., Beg, Subul, Lai, Jun, Martin, Jeffrey N., Hunt, Peter W., Henrich, Timothy J., Siliciano, Janet D., Siliciano, Robert F., Laird, Gregory M., Deeks, Steven G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101154/
https://ncbi.nlm.nih.gov/pubmed/32045386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.132997
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