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MetAP2 inhibition reduces food intake and body weight in a ciliopathy mouse model of obesity
The ciliopathies Bardet-Biedl syndrome and Alström syndrome are genetically inherited pleiotropic disorders with hyperphagia and obesity as primary clinical features. Methionine aminopeptidase 2 inhibitors (MetAP2i) have been shown in preclinical and clinical studies to reduce food intake, body weig...
Gorde:
| Argitaratua izan da: | JCI Insight |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Clinical Investigation
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7098713/ https://ncbi.nlm.nih.gov/pubmed/31877115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134278 |
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