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Comprehensive comparison of MetAP2 tissue and cellular expression pattern in lean and obese rodents

BACKGROUND: Methionine aminopeptidase 2 (MetAP2) cleaves the initiator methionine from nascent peptides during translation. In both preclinical and clinical studies, the pharmacological inhibition of MetAP2 in obese subjects results in the suppression of food intake and body weight loss. However, th...

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Detalhes bibliográficos
Publicado no:Diabetes Metab Syndr Obes
Main Authors: Han, Jing, Tang, Yang, Lu, Mingjian, Hua, Haiqing
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167978/
https://ncbi.nlm.nih.gov/pubmed/30319281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S171109
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