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Comprehensive comparison of MetAP2 tissue and cellular expression pattern in lean and obese rodents

BACKGROUND: Methionine aminopeptidase 2 (MetAP2) cleaves the initiator methionine from nascent peptides during translation. In both preclinical and clinical studies, the pharmacological inhibition of MetAP2 in obese subjects results in the suppression of food intake and body weight loss. However, th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Diabetes Metab Syndr Obes
Prif Awduron: Han, Jing, Tang, Yang, Lu, Mingjian, Hua, Haiqing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167978/
https://ncbi.nlm.nih.gov/pubmed/30319281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S171109
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