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Comprehensive comparison of MetAP2 tissue and cellular expression pattern in lean and obese rodents
BACKGROUND: Methionine aminopeptidase 2 (MetAP2) cleaves the initiator methionine from nascent peptides during translation. In both preclinical and clinical studies, the pharmacological inhibition of MetAP2 in obese subjects results in the suppression of food intake and body weight loss. However, th...
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| Veröffentlicht in: | Diabetes Metab Syndr Obes |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6167978/ https://ncbi.nlm.nih.gov/pubmed/30319281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S171109 |
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