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Mechanisms and Pathophysiological Significance of Sterile Inflammation during Acetaminophen Hepatotoxicity
Acetaminophen (APAP) is a widely used analgesic drug, which can cause severe liver injury after an overdose. The intracellular signaling mechanisms of APAP-induced cell death such as reactive metabolite formation, mitochondrial dysfunction and nuclear DNA fragmentation have been extensively studied....
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| Udgivet i: | Food Chem Toxicol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7098420/ https://ncbi.nlm.nih.gov/pubmed/32145352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2020.111240 |
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