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Acetaminophen Hepatotoxicity and Sterile Inflammation: the Mechanism of Protection of Chlorogenic Acid

Acetaminophen hepatotoxicity is characterized by extensive necrotic cell death and a sterile inflammatory response. A recent report suggested that a therapeutic intervention with chlorogenic acid, a dietary polyphenolic compound, protects against acetaminophen-induced liver injury by inhibiting the...

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Detalhes bibliográficos
Publicado no:Chem Biol Interact
Autor principal: Jaeschke, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872296/
https://ncbi.nlm.nih.gov/pubmed/26363200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2015.08.025
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